CD3 Mouse anti-Human, PE-Cy5, Clone: HIT3A, BD

Description

The HIT3a monoclonal antibody specifically binds to the human CD3 ε-chain, a 20 kDa subunit of the CD3/T cell antigen receptor complex found on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody can be mitogenic for T lymphocytes. The CD3 complex plays a role in signal transduction during antigen recognition by the T cell receptor for antigen. HIT3a antibody does not stain intracellular CD3 unlike the other CD3-specific clone, UCHT1.