1,8-Diazabicyclo[5.4.0]undec-7-ene (puriss., ≥99.0% (GC))

Description

Synonym: 2,3,4,6,7,8,9,10-Octahydropyrimidol[1,2-a]azepine, DBU, Pack Size : 50ml, 250ml & 1L

• CAS Number 6674-22-2

• Empirical Formula (Hill Notation) C₉H₁₆N₂

   

• Molecular Weight 152.24

   

Application 

1,8-Diazabicyclo[5.4.0] undec-7-ene can be used:
• To mediate the aza-Michael addition of nitrogen nucleophiles to α,β-unsaturated carbonyl compounds.
• As a nucleophilic catalyst for the esterification of carboxylic acid with dimethyl carbonate.
• As a bidentate ligand in copper (I) bromide mediated atom transfer radical polymerization of methyl methacrylate.
• As an efficient catalyst for the transesterification of dimethyl carbonate with glycerol.

Other Notes

Amidine base used for dehydrohalogenation reactions to olefins; Further important applications are e.g. esterification of carboxylic acids with alkyl halides; Alkylation and acylation of active methylene compounds.